Harrison Ford's wife of 18 years has filed for legal separation, citing irreconcilable differences.

Ford and his wife, screenwriter Melissa Mathison Ford, have been living apart since October 2000. They declined to comment on the filing in Los Angeles. "The only statement they have is that Melissa filed for separation from Harrison and the couple remain amicable," said Patricia McQueeney, Ford's agent.

Mathison is seeking joint custody of their son, Malcolm, 14, and daughter, Georgia, 11, according to the petition.

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