SEATTLE — Bartolo Colon and Vladimir Guerrero got the Anaheim Angels off to a fast start.
Colon won his Anaheim debut and Troy Glaus homered twice, leading the Angels to a 10-5 victory over the Seattle Mariners in their season opener Tuesday.
Guerrero, also playing his first game with Anaheim, hit a two-run double off the center-field wall to put the Angels ahead 10-1 in the eighth. He went 1-for-4 with a walk and a run scored.
The new-look Angels roughed up 21-game winner Jamie Moyer, who was knocked out in the sixth inning.
Guerrero and Colon signed last winter with the Angels, who hope their heralded free-agent pickups carry them back to the playoffs after winning the 2002 World Series.
Colon held Seattle to an unearned run and five hits in six innings. He struck out five and allowed just one baserunner after the second inning.
He didn't issue any walks, despite facing a full count eight times. And Anaheim's powerful lineup finished with 12 hits.
Jose Molina hit a solo home run in the second, and Adam Kennedy drove in another run with a sixth-inning single.
Glaus sent a 3-0 pitch from Moyer an estimated 414 feet to straightaway center in the fourth, a solo shot that put Anaheim ahead for good at 2-1. It was his first career homer at Safeco Field.
The next time Glaus stepped up, Guerrero had walked and Garret Anderson had singled. Glaus drove an 0-1 pitch 421 feet to nearly the same spot as his first home run for a three-run shot.
It was his 17th career multihomer game, but first against Seattle.
RED SOX 4, ORIOLES 1: At Baltimore, Curt Schilling allowed one run over six innings to win his Boston debut and Kevin Millar homered, leading the Red Sox past the Baltimore Orioles. It was the first win with the Red Sox for manager Terry Francona, and Lee Mazzilli's initial loss as manager of the Orioles.
Boston avoided its first 0-2 start since 1996. Keith Foulke got three outs for his first save with the Red Sox.
Baltimore starter Eric DuBose (0-1) allowed three runs and four hits in 5 1/3 innings.
DEVIL RAYS 9, YANKEES 4: At St. Petersburg, Fla., Alex Rodriguez hit his first home run for the New York Yankees, but Mike Mussina couldn't hold an early four-run lead against Tampa Bay.
Victor Zambrano gave up the first-inning homer to Rodriguez and another to Gary Sheffield, then found a way to keep the rest of the Yankees' powerful lineup quiet, beating the defending AL champions for the second time this season.
TIGERS 7, BLUE JAYS 3: At Toronto, Detroit lost slugger Dmitri Young to a broken right leg, but they beat Toronto to open 2-0 for the first time since 1986.
Mike Maroth won his first start of the season in the same ballpark where he lost his 20th game last year, and Ivan Rodriguez hit a two-run double off loser Miguel Batista. Carlos Guillen homered and drove in two runs.
ATHLETICS 3, RANGERS 1: At Oakland, Jermaine Dye hit a two-run homer and Mark Mulder looked like his old self on the mound in leading the Athletics to a victory over the Texas Rangers.
TWINS 7, INDIANS 6, 15 innings: At Minneapolis, Jacque Jones hit a tying homer with two outs in the ninth inning, and Jose Offerman's bases-loaded single in the 15th gave Minnesota a 7-6 victory over Cleveland. Cleveland's bullpen blew another late lead, and Minnesota finally scored against losing pitcher Jake Westbrook in the 15th after wasting several earlier chances.