Eli Manning, Giants QB, was 18-of-33 for 251 yards and threw a TD pass in his ninth straight game in a 24-6 victory at the 49ers.
Michael Vick, Falcons QB, went 22-for-31 for a season-high 228 yards and one touchdown, and added 38 yards on eight rushes in a 17-10 win at Miami.
Larry Johnson, Chiefs RB, who had 107 yards and two touchdowns on 22 carries, including a 1-yard dive on the final play for a 27-23 victory over Oakland.
Curtis Martin, Jets RB, had 21 carries for 72 yards against San Diego and became the 16th player in NFL history to score 100 touchdowns.
Steve Smith, Panthers WR, scored once and had five catches for 106 yards in a 34-14 rout at Tampa Bay.
LaDainian Tomlinson, Chargers RB, had 25 carries for 107 yards and a career-high four TDs in leading San Diego over the Jets 31-26.
Shaun Alexander, Seahawks RB, gained 173 yards on 23 carries, including touchdown runs of 88 and 14 yards, in beating the Cardinals 33-19.
Drew Brees, Chargers QB, led a 31-26 victory over the Jets with 270 yards passing and one TD, going 20-of-27.
Antonio Gates, Chargers WR, had eight catches for 132 yards in a 31-26 win over the Jets.