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Colorado quarterback Jordan Webb, left, passes under pressure from Southern California linebacker Lamar Dawson during the first half of an NCAA college football game, Saturday, Oct.20, 2012, in Los Angeles. Mark J. Terrill, Associated Press
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Southern California wide receiver Marqise Lee, right, catches pass in route to a touchdown as Colorado linebacker Jon Major looks on during the first half of their NCAA college football game, Saturday, Oct.20, 2012, in Los Angeles. Mark J. Terrill, Associated Press
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Colorado quarterback Jordan Webb, left, is sacked by Southern California linebacker Hayes Pullard during the first half of an NCAA college football game, Saturday, Oct. 20, 2012, in Los Angeles. Mark J. Terrill, Associated Press
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Southern California wide receiver Robert Woods, right, catches a pass for a touchdown as Colorado defensive back Kenneth Crawley defends during the first half of an NCAA college football game, Saturday, Oct. 20, 2012, in Los Angeles. Mark J. Terrill, Associated Press
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Southern California quarterback Matt Barkley reacts after throwing a touchdown pass during the first half of an NCAA college football game against Colorado, Saturday, Oct.20, 2012, in Los Angeles. Mark J. Terrill, Associated Press
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Southern California safety Drew McAllister intercepts a pass in the end zone during the first half of an NCAA college football game against Colorado, Saturday, Oct.20, 2012, in Los Angeles. Mark J. Terrill, Associated Press
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Southern California quarterback Matt Barkley passes during the first half of an NCAA college football game against Colorado, Saturday, Oct.20, 2012, in Los Angeles. Mark J. Terrill, Associated Press
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Southern California wide receiver Robert Woods, right, catches a pass for a touchdown as Colorado defensive back Kenneth Crawley defends during the first half of an NCAA college football game, Saturday, Oct.20, 2012, in Los Angeles. With that catch, Woods Mark J. Terrill, Associated Press
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Southern California safety Drew McAllister recovers a fumble by Colorado fullback Christian Powell, left, during the first half of an NCAA college football game, Saturday, Oct.20, 2012, in Los Angeles. Mark J. Terrill, Associated Press
By Associated Press

LOS ANGELES — Matt Barkley threw for 298 yards and six touchdowns while setting Southern California's career record for TD passes, and Robert Woods caught a school-record four scoring passes while also surpassing USC's career receptions mark in the 11th-ranked Trojans' 50-6 victory over Colorado on Saturday.

Barkley and Woods climbed atop the Trojans' record books during the most prolific day of their three-year partnership at USC (6-1, 4-1 Pac-12), connecting on scoring throws of 39, 29, 17 and 3 yards in the first 35 minutes against hapless Colorado (1-6, 1-3).

Barkley hit Woods with his 100th career TD pass in the second quarter to surpass Matt Leinart's USC and conference records. Woods passed Dwayne Jarrett on USC's career receptions list a few minutes later with his 217th career catch, going 17 yards for another TD.

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