MILAN — Tottenham had two goals disallowed in a 0-0 draw at home to Serie A joint leader Lazio in their opening game of the Europa League group stage on Thursday, while defending champion Atletico Madrid cruised to a 3-0 win at Hapoel Tel-Aviv.
United States international Clint Dempsey had a goal ruled out for offside halfway through the first period, before Steven Caulker saw his header struck off for his push on Lazio's Stefano Mauri.
Alvaro Gonzalez hit the post in the first half for Lazio, which failed to win for the first time this season.
In Israel, Cristian Rodriguez, Diego Costa and Raul Garcia all scored as Atletico made easy work of Hapoel, despite playing without star striker Radamel Falcao, who was rested for the Group B opener.
Elsewhere, three-time winner Liverpool beat Young Boys 5-3 in a thrilling match in Switzerland, Inter Milan needed a last-minute equalizer to draw 2-2 at home to Rubin Kazan and French league leader Marseille scraped a similar 2-2 draw at Fenerbahce.
Substitute Jonjo Shelvey scored Liverpool's fourth goal only 10 minutes after coming off the bench, before sealing the result two minutes from time. Teenager Andre Wisdom scored Liverpool's second on his debut, after an own goal by Juhani Ojala had given the Premier League side an early lead.
Sebastian Coates added Liverpool's other goal in his first European match.
Raphael Nuzzolo, Ojala and Gonzalo Zarate found the net for Young Boys, which briefly led in the second half.
Inter Milan, another club seeking a fourth title, needed a stoppage-time goal as it twice came from behind against Rubin. The Russian side took a shock lead when Inter goalkeeper Samir Handanovic saved Bibras Natkho's spot-kick, only for the rebound to fall to Aleksandr Ryazantsev, who lashed it home.
Teenager Marko Livaja leveled with his first goal for Inter but Salomon Rondon looked to have given Rubin a historic win at San Siro before Yuto Nagatomo's equalizer.
Marseille had to score twice in the final eight minutes to rescue its draw in Turkey.
The French side, which has won all five of its league games this season, seemed to be heading for a surpise defeat following goals from Fenerbahce's Caner Erkin and Alex.
However, Mathieu Valbuena pulled one back for the Ligue 1 team eight minutes from time before Andre Ayew sent the vociferous home fans into despair with the final kick of the game.
Udinese also snatched a 1-1 draw at the very end, Antonio Di Natale's stoppage-time strike rescuing a point for the Serie A side against big-spending Russian club Anzhi Makhachkala.
Lacina Traore had given Anzhi a halftime lead.
Meanwhile, last season's runner-up Athletic Bilbao was held to a 1-1 draw at home by Hapoel Kiryat Shmona.
Adrian Rochet gave the Israeli champion a surprise lead in the 14th minute but Markel Susaeta leveled five minutes from halftime.
Striker Fernando Llorente was introduced at the start of the second half to loud boos from the home fans, who are unhappy with his decision to seek a move in January.
Athletic has lost early ground in Group I, after Lyon beat Sparta Prague 2-1.
Napoli cruised to a 4-0 win over AIK Stockholm, with Edu Vargas scoring a hat-trick — his first goals for the Italian club.
Napoli's Marek Hamsik was sent off in the closing stages but there was still time for Blerim Dzemaili to add a fourth.