Does the Centers for Disease Control and Prevention have a preference for your booster shot? No, not really.

On Friday, the CDC said it has endorsed COVID-19 vaccine booster shots for the Moderna and Johnson & Johnson COVID-19 vaccines, which now opens the door for millions of more people to receive COVID-19 booster shots.

  • The CDC said people can also mix and match their COVID-19 vaccine boosters. So if you got the two-shot Moderna regimen last spring, you can now get a Pfizer booster shot if you prefer.
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Dr. Rochelle Walensky, the director of the CDC, said on the “Today” show there isn’t a preference on which booster shot to get. She also said the CDC doesn’t have a preference as to whether you should switch your vaccine or not.

  • “We do not indicate a preference … it really is fine to get a different vaccine,” she said.

So which booster is best? Well, there is data that offers a glimpse into how the vaccines are different. A recent study found that the Moderna and Pfizer COVID-19 vaccine boosters shots produced stronger immunity than the Johnson & Johnson booster shot.

  • The best combo for creating immunity was those who got the Moderna two-dose vaccine regimen and a Moderna booster shot.
  • Pfizer’s shot with a Moderna booster had the second-best immunity response.
  • Moderna’s two-dose vaccine with Pfizer’s booster shot also produced high immunity.