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Here’s what it’s like to get a COVID-19 vaccine booster shot (from a different vaccine)

Virus expert Joseph Hyser got a recent booster shot from a different vaccine. Here are his side effects

Vials of Moderna’s COVID-19 vaccines sit on a table.
Vials of Moderna’s COVID-19 vaccines sit on a table at the Mountain America Exposition Center in Sandy on Tuesday, May 18, 2021.
Scott G Winterton, Deseret News

Virus expert Joseph Hyser has revealed what it’s like to get a third shot of the coronavirus vaccine. And his third shot came from a different developer than the first two.

Can you mix Pfizer and Moderna shots?

Business Insider reports that Hyser originally got both doses of the Pfizer COVID-19 vaccine. Recently, he got involved in a new COVID-19 vaccine mix-and-match study, which looks to see how boosters work and whether or not it’s safe to mix vaccines.

  • For example, the study wants to see if someone who got the full Pfizer vaccine would see benefits from getting a Moderna booster shot, especially since both vaccines are mRNA vaccines.

Hyser did just that. He got the third booster shot from the Moderna vaccine rather than the Pfizer.

What side effects come from Pfizer and Moderna together?

Hyser said he had “similar types of side effects,” according to Business Insider. However, he said these side effects were “a little bit more obvious with the Moderna.”

  • Hyser said ibuprofen and resting helped the side effects from the third shot go away. He told Business Insider that he had chills, arm soreness and it felt like he had taken a “hard punch in the shoulder” after the third shot.
  • “With the booster, it was a little bit more severe,” he said.

When will we have to get our third COVID-19 shots?

Questions about a third COVID-19 booster shot remain unanswered as vaccine developers look to understand how long immunity lasts from the first round of shots, as I wrote for the Deseret News.

However, CEOs from Moderna and Pfizer — the two major developers of the common COVID-19 vaccines — told Axios that the “booster” shots will be available and necessary by fall 2021.

  • “The data that I see coming, they are supporting the notion that likely there will be a need for a booster somewhere between eight and 12 months,” Pfizer CEO Albert Bourla said, according to Axios.

And Dr. Anthony Fauci, the White House chief medical adviser on COVID-19, told Axios that the third shot will be needed.

  • “I think we will almost certainly require a booster sometime within a year or so after getting the primary (shot) because the durability of protection against coronaviruses is generally not lifelong,” Fauci said, according to Axios.